LNA-T PHOSPHORAMIDITE

LNA-T PHOSPHORAMIDITE - Names and Identifiers

Name	DMT-LOCT AMIDITE 0.25G, ABI, SINGLE
Synonyms	LNA-T PHOSPHORAMIDITE DMTR-LNA-5MEU-3-CED-PHOSPHORAMIDITE DMTr-LNA-5MeU-3-CED-phosphoramidite 2'-O-4'-C-Locked-Tr-CE-Phosphoramidite 5'-O-(4, 4'-dimethoxytrityl)-2'-O-4'-C-Locked-thymidine-3'-cyanoethyl Phosphoramidite 5'-O-[BIS(4-METHOXYPHENYL)PHENYLMETHYL]-2'-O-4'-C-LOCKED-THYMIDINE-3'-CE PHOSPHORAMIDITE 2,4(1H,3H)-Pyrimidinedione, 1-[2,5-anhydro-4-C-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-α-L-lyxofuranosyl]-5-methyl-
CAS	206055-75-6

LNA-T PHOSPHORAMIDITE - Physico-chemical Properties

Molecular Formula	C41H49N4O9P
Molar Mass	772.84
pKa	9.46±0.10(Predicted)
Storage Condition	Room Temprature

LNA-T PHOSPHORAMIDITE - Introduction

DMT-LOCT AMIDITE 0.25G, ABI, SINGLE is an organic compound. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: Commonly, this compound is a white crystalline solid.
-Solubility: It has better solubility in some organic solvents, such as alcohols and esters.
-Melting point: About 100-110 ° C.
-Toxicity: The toxicity of the compound is low, but it is still necessary to pay attention to the correct use and storage.

Use:
-As one of the commonly used reagents in organic synthesis, it can participate in a variety of organic reactions, such as the transesterification of carboxylic esters and nucleophilic substitution reactions.
-In the pharmaceutical industry, it can be used as an intermediate for the synthesis and modification of drug molecules.
-In scientific research, it can also be used as a catalyst or ligand in organic synthesis.

Preparation Method:
-The preparation method of this compound involves a multi-step reaction. Common synthetic routes include the use of specific reagents and the manipulation of temperature and time conditions.

Safety Information:
-When handling the compound, you need to take appropriate personal protective measures, such as wearing gloves and safety glasses, to avoid contact with skin and eyes.
-It should be operated in a well-ventilated place to avoid inhaling the dust or vapor of the compound.
-The compound should be stored and handled properly, complying with local chemical storage and waste disposal regulations.

Please note that for specific chemical substances, it is recommended to use them reasonably in a laboratory environment and strictly follow the corresponding safety procedures.

Last Update：2024-04-09 15:16:30